MXFX for Windows has a known bug and fails to initialize when processing 720/30p mxf files.
This bug is in the process of being fixed for the next update, but for now a simple workaround is as follows:
In the destination folder, create a new folder named 'card1.' Leave the MXFX Options set to the original destination folder (Do not set the destination to the 'card1' folder you created). Then click ok and start and MXFX should process the clip without a problem.
Usually, MXFX for Windows will automatically create this 'card1' folder in the destination folder, but due to the bug it has to be created manually.
If you have any questions please go to dvfilm.com/support.htm to place a support request.